Discover how to get to Panamá on a direct flight from South America

Panamá offers 706 weekly direct flights to 37 cities in South America, making your trip easy without the need for connections or inconveniences. Start planning your adventure.

Below, you will find a guide with information about the nearest airport to your destination in Panamá, flight frequencies from your country of origin, and the airlines that operate these routes.

Direct flights from:

Argentina, Bolivia, Brazil, Chile, Colombia, Ecuador, Guyana, Paraguay, Peru, Suriname, Uruguay, Venezuela

Colombia

Colorful Guatape town colonial style architecture due to its tiles on its facades

257 weekly flights to Panama City, Tocumen International Airport (PTY)

From Barranquilla: Ernesto Cortissoz Barranquilla International Airport (BAQ)
From Bogotá: El Dorado International Airport (BOG)
From Bucaramanga: Palonegro International Airport (BGA)
From Cali: Alfonso Bonilla Aragón International Airport (CLO)
From Cartagena: Rafael Núñez International Airport (CTG)
From Cúcuta: Camilo Daza International Airport (CUC)
From Medellín: Jose Maria Cordova International Airport (MDE)
From Pereira: Matecaña International Airport (PEI)
From San Andrés Island: Gustavo Rojas Pinilla International Airport (ADZ)
From Santa Marta: Simón Bolívar International Airpor (SMR)

26 weekly flights to Panama Pacific International Airport (BLB)

From Barranquilla: Ernesto Cortissoz Barranquilla International Airport (BAQ)
From Bogotá: El Dorado International Airport (BOG)
From Cali: Alfonso Bonilla Aragón International Airport (CLO)
From Cartagena: Rafael Núñez International Airport (CTG)
From Medellín: Jose Maria Cordova International Airport (MDE)

Airlines: Copa Airlines, Wingo, Avianca

Argentina

The Obelisk of Buenos Aires, a tall white monument, stands tall in the center of a busy city street. Buildings line the sides of the street, and an Argentine flag is visible flying from one of them.

91 weekly flights to Panama City, Tocumen International Airport (PTY)

From Buenos Aires: Ezeiza International Airport (EZE)
From Córdoba: Ingeniero Aeronáutico Ambrosio L.V. Taravella International Airport (COR)
From Rosario: Rosario – Islas Malvinas International Airport (ROS)
From Mendoza: El Plumerillo International Airport (MDZ)
From Salta: Martín Miguel de Güemes International Airport (SLA)
From San Miguel de Tucumán: Teniente General Benjamín Matienzo International Airport (TUC)

Airlines: Copa Airlines

Brazil

An aerial view of Rio de Janeiro, Brazil, featuring the iconic Christ the Redeemer statue atop Corcovado Mountain. The city is spread out below, with Guanabara Bay and Sugarloaf Mountain visible in the distance.

89 weekly flights to Panama City, Tocumen International Airport (PTY)

From São Paulo: São Paulo-Guarulhos International Airport (GRU)
From Rio de Janeiro: Galeão International Airport (GIG)
From Belo Horizonte: Aeropuerto Internacional Tancredo Neves (CNF)
From Brasilia: Brasilia International Airport (BSB)
From Manaus: Eduardo Gomes International Airport (MAO)
From Florianopolis: Florianópolis–Hercílio Luz International Airport(FLN)
From Porto Alegre: Salgado Filho International Airport (POA)
From Salvador de Bahía: Salvador Deputy Luís Eduardo Magalhães International Airport (SSA)