Arrive at Panama City’s Tocumen International Airport and kick off your adventure in this vibrant capital. Tour the Miraflores Locks — part of the Panama Canal, a marvel of modern engineering — later discover the charm of Casco Antiguo, the Colonial District of the City, and savor dinner at one of the Latam 50 Best restaurants.

Conclude the evening aboard your yacht anchored at Amador Causeway, and start your overnight sail to your next destination, framed by the dazzling lights of the majestic skyline. 

Experience legendary sportfishing in Piñas Bay, secluded and surrounded by lush Darien province rainforest, it is home to the world-famous Zane Grey Reef — a large underwater mountain that rises from the seafloor and peeks over the surface — and one of the most renowned fishing spots in the world, boasting over 300 world records in deep-sea fishing—more than any other place on Earth. 

Chase record-class black marlin, tuna, and roosterfish in deep blue waters surrounded by untouched jungle. These two days are a fisherman’s dream: high-adrenaline, world-renowned fish, and lush tropical scenery. 

After completing your adventure through the fisherman’s dream — Piñas Bay — cruise toward the heart of the Gulf of Panama, the stunning Las Perlas Archipelago — which comprises more than 200 uninhabited islands and islets for premium fishing trips all year long. You will have the opportunity to fish along the 20 Fathom Bank for sailfish and dorado on the way, or spend the day on the beautiful white-sand beaches or — during the right season — watching humpback whales, diving and admiring preserved nature and sea life.

If you’re after prize-winning yellowfin tuna, you’re in the right place — Pedasi, in the heart of Panamá’s Tuna Coast. Between March and August, this stretch of the Pacific comes alive with massive schools of tuna, giving anglers some of the best fishing action anywhere. Here, your catch is almost guaranteed — and often big.

Sail from shallow to deep waters and find an ocean teeming with life. With few sport-fishing boats in the area, you’ll have the sea (and the fight) mostly to yourself. 

Ready for a change of rhythm? Time to drop the fishing line for a bit and head to Playa Venao – a coastal town filled with a laid-back vibe, a world-class surfing community, restaurants with tasty gastronomy and an incredible nightlife. 

The south-facing beach is situated perfectly for south swells. But if you're into surfing, there's still plenty for you here: deep-sea fishing, snorkeling, diving, hiking, yoga and eco-spas. Playa Venao is the perfect mix between a coastal lifestyle and a wellness state of mind.

After a break from your fishing adventures, head to the Gulf of Montijo — a protected Ramsar Site covering more than 97,000 hectares of wetlands, mangroves, and coastal ecosystems. 

Recognized as both an artisanal and sport-fishing community, the gulf supports local livelihoods while protecting traditional fishing practices passed down for generations. Here, you can paddle through mangrove tunnels, spot birds, crocodiles, and even dolphins, or join a community-led eco-tour that helps preserve this unique marine landscape.

If you’re up for another adventure, head to Santa Catalina — a small fishing village turned world-class surf destination. Here, you’ll find a welcoming mix of boutique lodges, laid-back hospitality, a vibrant nightlife, and growing food scene that perfectly captures the spirit of Panamá’s Pacific coast.

Experience the thrill of fishing at Hannibal Bank, one of Panamá’s most famous deep-sea fishing areas, where ocean currents bring large schools of tuna, marlin, and sailfish close to the surface. 

Looking for a private beach and luxury accommodations? Choose to visit Isla Secas which offers easy access between the fishing adventures – in Hannibal Bank and Montuosa Island – and the comfort of unforgettable on-land experiences. 

And while you’re in the area, don’t miss the chance to visit Coiba National Park, a UNESCO World Heritage Site, one of Panamá’s must-see natural wonders — known for its incredible marine life and pristine nature. Today, it protects hundreds of species of fish, coral, turtles, and whale sharks, making it one of Panamá’s most extraordinary places to explore.

Conclude your journey in Boca Chica – a coastal town – located in the Gulf of Chiriqui. After disembarking at the tender dock, you have options: take a one-hour car trip to David International Airport (DAV | Enrique Malek) to catch your flight back to Panama City. 

If you are interested in knowing more about Boquete and exploring Tierras Altas – the vast and lush highlands of Panamá –  spend more time here, home to the world’s most valuable coffee, just 1–2 hours away by car. Looking for guidance or what to do? Find here a 13-day itinerary to get the most out of the land of coffee and adventure.